5 Easy Facts About testosterone Described
5 Easy Facts About testosterone Described
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在過程中加入鋅睪酮的合成份量。鋅是類固醇受體的運作有著重要影響，且是能使睪酮合成的酶的協助因素。
Testosterone could be a treatment for postmenopausal Gals assuming that They're proficiently estrogenized.[80]
Testosterone has several key steps. It offers adverse feedback inhibition about the secretion of gonadotropin-releasing hormone in the hypothalamus as well as secretion of luteinizing hormone in the pituitary gland. It also directs the development on the embryonic Wolffian ducts in the vas deferens (ductus deferens) and seminal vesicles and stimulates the development of muscle mass and bone.
利用睪酮的男性化作用，跨性别男性（即由女性經由變性成為男性）會以睪酮作為替代，以維持至一般正常男性的睪酮水平。同樣地，跨性别女性會使用藥物抑制睪酮的生成，以讓雌激素發揮效用。
Generally, androgens for example testosterone endorse protein synthesis and therefore advancement of tissues with androgen receptors.[16] Testosterone may be referred to as possessing anabolic and androgenic (virilising) outcomes, though these categorical descriptions are fairly arbitrary, as There is certainly quite a lot of mutual overlap amongst them.[17] The relative potency of those consequences can rely upon many factors and is particularly a topic of ongoing research.
Androgen receptors arise in numerous vertebrate human body process tissues, and both equally males and females react in the same way to very similar degrees. Considerably differing amounts of testosterone prenatally, at puberty, and all through lifestyle account for just a share of Organic distinctions in between males and females.
精原细胞 · 精母细胞发生 · 精母细胞 · 精细胞发生 · 精细胞 · 精子形成 · 精子
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精囊 · 精腺排泄管 · 攝護腺（尿道嵴／精阜／攝護腺小囊／射精管 · 攝護腺窦／攝護腺小管） · 尿道球腺
Completion of bone maturation and termination of advancement. This happens indirectly by means of estradiol metabolites and for this reason far more progressively in Males than Women of all ages.
[147] The T-receptor or DHT-receptor advanced undergoes a structural adjust that allows it to move into the cell nucleus and bind Special Deal on to distinct nucleotide sequences on the chromosomal DNA. The parts of binding are termed hormone response features (HREs), and influence transcriptional exercise of specific genes, producing the androgen results.
Comparable to other steroid hormones, testosterone exists in serum in two forms. Most testosterone within the serum is sure to intercourse hormone-binding globulin and also to albumin, whilst the remaining amount of money (about 1 %) is totally free, or unbound. No cost testosterone is in equilibrium with certain testosterone in order that when totally free testosterone enters cells, some certain testosterone is immediately freed.
[70] This reaction engages penile reflexes (like erection and ejaculation) that support in sperm Level of competition when multiple male is present in mating encounters, making it possible for for more creation of thriving sperm and an increased possibility of replica.
Testosterone is provided on earth Wellness Organization's listing of crucial medicines, which can be The most crucial medications wanted inside of a primary wellness method.